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LHB 抗体

LHB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal LHb-1214 unconjugated
产品编号 ABIN6939960
发货至: 中国
  • 抗原 See all LHB 抗体
    LHB (Luteinizing Hormone beta Polypeptide (LHB))
    适用
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    宿主
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    小鼠
    克隆类型
    • 38
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    单克隆
    标记
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    This LHB antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC), Staining Methods (StM)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant beta sub-unit of human LH
    克隆位点
    LHb-1214
    亚型
    IgG1 kappa
    Top Product
    Discover our top product LHB Primary Antibody
  • 应用备注

    Positive Control: Anterior Pituitary.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL, 30 min RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    LHB (Luteinizing Hormone beta Polypeptide (LHB))
    别名
    LHB (LHB 产品)
    别名
    CGB4 antibody, LSH-B antibody, hLHB antibody, LH antibody, LH-B antibody, LSH-beta antibody, cgb4 antibody, hlhb antibody, xlhb antibody, lhb-A antibody, lsh-b antibody, LH/CG-beta antibody, LHB antibody, LSH-B/CG-B antibody, Lutropin beta chain antibody, lhb1 antibody, lhbeta1 antibody, zgc:92312 antibody, lhb antibody, luteinizing hormone beta polypeptide antibody, luteinizing hormone beta antibody, lutropin subunit beta-like antibody, luteinizing hormone, beta polypeptide antibody, luteinizing hormone beta polypeptide L homeolog antibody, LHB antibody, Lhb antibody, lhb antibody, LOC106838274 antibody, lhb.L antibody
    背景
    Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule, two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
    分子量
    22kDa
    基因ID
    3972
    UniProt
    P01229
    途径
    Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity, C21-Steroid Hormone Metabolic Process
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