MEG3 抗体 (AA 23-561)
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Quick Overview for MEG3 抗体 (AA 23-561) (ABIN7872547)
抗原
See all MEG3 (FAM129B) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-561
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原理
- FAM129B Antibody / MINERVA / NIBAN2
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纯化方法
- Affinity purified
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免疫原
- An E. coli-derived human protein (amino acids K23-K561) was used as the immunogen for the FAM129B antibody.
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亚型
- IgG
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anti-Family with Sequence Similarity 129, Member B (FAM129B) antibody
FAM129B 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (AA 710-714) antibodyFAM129B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (Ser712) antibodyFAM129B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (C-Term) antibodyFAM129B 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the FAM129B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FAM129B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MEG3 (FAM129B) (Family with Sequence Similarity 129, Member B (FAM129B))
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别名
- FAM129B
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背景
- FAM129B/Niban-like protein 1 (family with sequence similarity 129, member B) belongs to a poorly characterized family of Niban proteins that also includes FAM129A/Niban and FAM129C/Niban-like protein 2. FAM129A/Niban is implicated in the ER stress response and is upregulated at the protein level in thyroid carcinoma. FAM129C/Niban-like protein 2 is preferentially expressed in B-cells and is one of five biomarkers upregulated in whole blood from patients with colorectal carcinoma. FAM129B is broadly expressed and has been shown to be a downstream target of B-Raf in melanoma cells. Though FAM129B does not appear to regulate cell growth and division, phosphorylation of FAM129B by B-Raf is essential for the invasive potential of melanoma and non-melanoma cell lines. Deletion of FAM129B in melanoma cells significantly impairs B-Raf/MEK/Erk-dependent invasion into the extracellular matrix.
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UniProt
- Q96TA1
抗原
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