MEG3 抗体 (pSer679, pSer683)
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- 抗原 See all MEG3 (FAM129B) 抗体
- MEG3 (FAM129B) (Family with Sequence Similarity 129, Member B (FAM129B))
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抗原表位
- pSer679, pSer683
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MEG3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应
- 小鼠
- 纯化方法
- Anti-Phospho-Ser679/683 FAM129B Antibody is directed against human FAM129B protein phosphorylated at S679 and S683. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated FAM129B. Minimal reactivity occurs against non-phosphorylated FAM129B. Reactivity against FAM129B occurs from mouse sources. However, reactivity is also expected against human and non-human primate based on 100% sequence homology.
- 免疫原
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Immunogen: Anti-Phospho-Ser679/683 FAM129B Antibody was produced in rabbits by repeated immunizations with a synthetic phospho-peptide corresponding to amino acid residues surrounding Ser679/683 of human FAM129B conjugated to KLH.
Immunogen Type: Peptide
- 亚型
- IgG
- Top Product
- Discover our top product FAM129B Primary Antibody
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anti-Family with Sequence Similarity 129, Member B (FAM129B) antibody
FAM129B 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) antibodyFAM129B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) antibodyFAM129B 适用: 人, 小鼠, 大鼠 WB, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (pSer679), (pSer683) antibodyFAM129B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (AA 710-714) antibodyFAM129B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (Ser712) antibodyFAM129B 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 129, Member B (FAM129B) (C-Term) antibodyFAM129B 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 犬, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Application Note: Anti-Phospho-Ser679/683 FAM129B Antibody is suitable for Western Blots and is specific for the ~83 kDa FAM129B phosphorylated at Ser679/683. Immunolabeling is blocked by preadsorption of antibody with the phospho-peptide that was used to generate the antibody but not by the corresponding dephospho-peptide.
ELISA Dilution: 1:10,000
Western Blot Dilution: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5
Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol
- 储存液
- Without preservative
- 储存条件
- RT,-20 °C
- 储存方法
- Store vial at -20° C prior to opening in undiluted aliquots. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilut
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- 抗原
- MEG3 (FAM129B) (Family with Sequence Similarity 129, Member B (FAM129B))
- 别名
- FAM129B (FAM129B 产品)
- 别名
- C9orf88 antibody, MEG-3 antibody, MINERVA antibody, OC58 antibody, bA356B19.6 antibody, MGC82535 antibody, 9130404D14Rik antibody, RGD1307018 antibody, fam129b antibody, zgc:158319 antibody, family with sequence similarity 129 member B antibody, family with sequence similarity 129 member B S homeolog antibody, family with sequence similarity 129, member B antibody, family with sequence similarity 129, member Ba antibody, FAM129B antibody, fam129b.S antibody, fam129b antibody, Fam129b antibody, fam129ba antibody
- 背景
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Synonyms: Niban-like protein 1, Meg-3, Melanoma invasion by ERK, MINERVA, Protein FAM129B
Background: FAM129B, also known as Niban-like protein 1, belongs to a poorly characterized protein family with unknown category and function. Increased expression of the Niban gene has been observed in renal carcinomas. Suppression of FAM129B expression in HeLa cells has been seen to promote apoptosis, suggesting that it can modulate cell death signaling, and may be involved in the ER stress response. FAM129B is also up-regulated in various types of thyroid tumors and Hashimoto's thyroiditis. It has been suggested that the MAP kinase dependent phosphorylation of FAM129B is important in controlling melanoma cells, as inhibition of B/Raf/MKK/ERK in melanoma cells represses invasion. It is believed that phosphorylated FAM129B not only derepresses invasion, but also regulates events that promote invasion. FAM129B pS679/683 Antibody is ideal for researchers interested in cancer research.
Gene Name: FAM129B
- 基因ID
- 64855
- UniProt
- Q96TA1
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