STEAP2 抗体 (AA 229-258)
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Quick Overview for STEAP2 抗体 (AA 229-258) (ABIN7872430)
抗原
See all STEAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 229-258
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原理
- STEA2 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 229-258 from the human protein was used as the immunogen for the STEA2 antibody.
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亚型
- IgG
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应用备注
- The stated application concentrations are suggested starting points. Titration of the STEA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the STEA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- STEAP2 (STEAP Family Member 2, Metalloreductase (STEAP2))
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别名
- STEA2
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背景
- This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
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UniProt
- Q8NFT2
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途径
- Transition Metal Ion Homeostasis
抗原
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