FGFR2 抗体 (AA 22-821)
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Quick Overview for FGFR2 抗体 (AA 22-821) (ABIN7872337)
抗原
See all FGFR2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-821
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原理
- Fibroblast growth factor receptor 2 Antibody / FGFR2
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids R22-T821) was used as the immunogen for the Fibroblast growth factor receptor 2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Fibroblast growth factor receptor 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Fibroblast growth factor receptor 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
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别名
- Fibroblast growth factor receptor 2
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背景
- Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.
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UniProt
- P21802
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
抗原
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