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MLF1 抗体 (AA 215-244)

This 兔 多克隆 antibody specifically detects MLF1 in WB, FACS 和 IHC (p). It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN7872230
发货至: 中国
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Quick Overview for MLF1 抗体 (AA 215-244) (ABIN7872230)

抗原

See all MLF1 抗体
MLF1 (Myeloid Leukemia Factor 1 (MLF1))

适用

  • 65
  • 45
  • 20
  • 1
  • 1
人, 小鼠

宿主

  • 62
  • 5

克隆类型

  • 64
  • 3
多克隆

标记

  • 36
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MLF1 antibody is un-conjugated

应用范围

  • 54
  • 22
  • 20
  • 16
  • 13
  • 8
  • 7
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 13
    • 8
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 215-244

    原理

    MLF1 Antibody / Myeloid leukemia factor 1

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 215-244 from the human protein was used as the immunogen for the MLF1 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the MLF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the MLF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    MLF1 (Myeloid Leukemia Factor 1 (MLF1))

    别名

    MLF1

    背景

    MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

    UniProt

    P58340
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