MUC2 抗体 (AA 21-255)
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Quick Overview for MUC2 抗体 (AA 21-255) (ABIN7872156)
抗原
See all MUC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-255
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原理
- Mucin 2 Antibody / MUC2
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids S21-C255) was used as the immunogen for the Mucin 2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Mucin 2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Mucin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MUC2 (Mucin 2, Oligomeric Mucus/gel-Forming (MUC2))
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别名
- Mucin 2
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背景
- Mucin 2, also known as MUC2, is a protein that in humans is encoded by the MUC2 gene. This gene encodes a member of the mucin protein family. It is mapped to 11p15.5. Mucin 2 is particularly prominent in the gut where it is secreted from goblet cells in the epithelial lining into the lumen of the large intestine. There, mucin 2, along with small amounts of related-mucin proteins, polymerizes into a gel of which 80 % by weight is oligosaccharide side-chains that are added as post-translational modifications to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the intestinal epithelium. The primary function of the MUC2 gene product is to provide a protective barrier between the epithelial surfaces and the gut lumen. There is decreased expression of MUC2 in colonic cancer and defective polymerization of secreted mucin in ulcerative colitis.
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UniProt
- Q02817
抗原
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