SFRP1 抗体 (AA 204-314)
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Quick Overview for SFRP1 抗体 (AA 204-314) (ABIN7872090)
抗原
See all SFRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 204-314
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原理
- SFRP1 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Amino acids A204-K314 from the human protein were used as the immunogen for the SFRP1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the SFRP1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the SFRP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SFRP1 (Secreted Frizzled-Related Protein 1 (SFRP1))
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别名
- SFRP1
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背景
- Secreted frizzled-related protein 1, also known as SFRP1, is a protein which in humans is encoded by the SFRP1 gene. It is mapped to 8p11.21. This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling, epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
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UniProt
- Q8N474
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途径
- WNT signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Negative Regulation of Hormone Secretion, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of fat Cell Differentiation
抗原
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