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IDO2 抗体 (AA 200-350)

The 小鼠 单克隆 anti-IDO2 antibody is suitable to detect IDO2 in samples from 人. It has been validated for WB, ELISA 和 IHC (p).
产品编号 ABIN7871973
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IDO2 抗体 (AA 200-350) (ABIN7871973)

抗原

See all IDO2 抗体
IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IDO2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

IDO2-2638
  • 抗原表位

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    AA 200-350

    原理

    INDOL1 Antibody / IDO2

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 200-350 was used as the immunogen for the INDOL1 antibody.

    亚型

    IgG, kappa
  • 应用备注

    Optimal dilution of the INDOL1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the INDOL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))

    别名

    INDOL1

    背景

    IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.

    UniProt

    Q6ZQW0
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