IDO2 抗体 (AA 200-350)
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Quick Overview for IDO2 抗体 (AA 200-350) (ABIN7871969)
抗原
See all IDO2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 200-350
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原理
- IDO2 Antibody / INDOL1
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 200-350 was used as the immunogen for the IDO2 antibody.
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亚型
- IgG, kappa
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应用备注
- Optimal dilution of the IDO2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.2 mg/mL
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缓冲液
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IDO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- IDO2 (Indoleamine 2,3-Dioxygenase 2 (IDO2))
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别名
- IDO2
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背景
- IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.
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UniProt
- Q6ZQW0
抗原
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