KISS1 抗体 (AA 20-52)
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北京 101111
Quick Overview for KISS1 抗体 (AA 20-52) (ABIN7871877)
抗原
See all KISS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-52
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原理
- KiSS-1 Antibody / KISS1
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 20-52 from the human protein was used as the immunogen for the KiSS-1 antibody.
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亚型
- Ig Fraction
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anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 46-145) antibody
KISS1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-52) antibodyKISS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53797 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (Internal Region) antibodyKISS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 115-145) antibodyKISS1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB53799 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) antibodyKISS1 适用: 人 IHC 宿主: 兔 Monoclonal HMV3972 unconjugated Recombinant Antibody
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-126) antibodyKISS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) antibodyKISS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-138) antibodyKISS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the KiSS-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the KiSS-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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别名
- KiSS-1
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背景
- Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine- tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
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UniProt
- Q15726
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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