DDIT4 抗体 (AA 20-49)
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Quick Overview for DDIT4 抗体 (AA 20-49) (ABIN7871875)
抗原
See all DDIT4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-49
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原理
- REDD-1 Antibody / DDIT4
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 20-49 from the human protein was used as the immunogen for the REDD-1 antibody.
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亚型
- Ig Fraction
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anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 20-49), (N-Term) antibody
DDIT4 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB12592 unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 198-227), (C-Term) antibodyDDIT4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB11618 unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-232) antibodyDDIT4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-232) antibodyDDIT4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (N-Term) antibodyDDIT4 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-50) antibodyDDIT4 适用: 人 IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) antibodyDDIT4 适用: 人 WB, IP, ICC 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 45-94) antibodyDDIT4 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (AA 1-50) antibodyDDIT4 适用: 人 WB, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA-Damage-Inducible Transcript 4 (DDIT4) (C-Term), (N-Term) antibodyDDIT4 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the REDD-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the REDD-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
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别名
- REDD-1
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背景
- REDD-1 is a novel transcriptional target of p53 induced following DNA damage. During embryogenesis, REDD-1 expression mirrors the tissue-specific pattern of the p53 family member p63, and TP63 null embryos show virtually no expression of REDD-1, which is restored in mouse embryo fibroblasts following p63 expression. In differentiating primary keratinocytes, TP63 and REDD-1 expression are coordinately downregulated, and ectopic expression of either gene inhibits in vitro differentiation. REDD1 appears to function in the regulation of reactive oxygen species (ROS), TP63 null fibroblasts have decreased ROS levels and reduced sensitivity to oxidative stress, which are both increased following ectopic expression of either TP63 or REDD-1. Thus, REDD-1 encodes a shared transcriptional target that implicates ROS in the p53-dependent DNA damage response and in p63-mediated regulation of epithelial differentiation.
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UniProt
- Q9NX09
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途径
- Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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