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MPG 抗体 (AA 20-298)

This 兔 多克隆 antibody specifically detects MPG in WB 和 ELISA. It exhibits reactivity toward 人.
产品编号 ABIN7871858
发货至: 中国
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Quick Overview for MPG 抗体 (AA 20-298) (ABIN7871858)

抗原

See all MPG 抗体
MPG (N-Methylpurine-DNA Glycosylase (MPG))

适用

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宿主

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克隆类型

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多克隆

标记

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This MPG antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 20-298

    原理

    DNA-3-methyladenine glycosylase Antibody / MPG / AAG

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids Q20-A298) was used as the immunogen for the DNA-3-methyladenine glycosylase antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the DNA-3-methyladenine glycosylase antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the DNA-3-methyladenine glycosylase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MPG (N-Methylpurine-DNA Glycosylase (MPG))

    别名

    DNA-3-methyladenine glycosylase

    背景

    MPG (N-methylpurine-DNA glycosylase) also known as MDG, 3-METHYLADENINE DNA GLYCOSYLASE, 3MeAde DNA GLYCOSYLASE, AAG and APNG is a protein expressed in all cell lines and tissues examined, but was found at particularly high levels in a colon adenocarcinoma cell line(HT29). The completely characterized human MPG gene was found to span 7 to 8 kb of genomic DNA and to be localized 75 kb upstream of the embryonic zeta-globin gene. To assess the contribution of Apng to the repair of several mutagenic lesions in vivo,Hang et al.(1997)biochemically analyzed cell-free extracts of tissues from mice with a targeted deletion of the Apng gene. Following treatment with DNA-methylating agents, increased persistence of 7-methylguanine (meG) was found in liver sections of APNG knockout mice in comparison with wildtype mice, demonstrating an in vivo phenotype for the APNG-null animals.

    UniProt

    P29372

    途径

    DNA Damage Repair
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