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METAP2 抗体 (AA 191-464)

The 兔 多克隆 anti-METAP2 antibody is suitable to detect METAP2 in samples from 斑马鱼. It has been validated for WB 和 IHC (p).
产品编号 ABIN7871667
发货至: 中国
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Quick Overview for METAP2 抗体 (AA 191-464) (ABIN7871667)

抗原

See all METAP2 抗体
METAP2 (Methionyl Aminopeptidase 2 (METAP2))

适用

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斑马鱼

宿主

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克隆类型

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多克隆

标记

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This METAP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 191-464

    原理

    Zebrafish Metap2 Antibody / Methionine aminopeptidase 2 / Isoforms a & b

    纯化方法

    Antigen affinity chromatography

    免疫原

    An E.coli-derived zebrafish Metap2a/b recombinant protein (amino acids E191-R464) was used as the immunogen for the Zebrafish Metap2 antibody. This antibody will detect the a and b isoforms.

    亚型

    Ig Fraction
  • 应用备注

    Optimal dilution of the Zebrafish Metap2 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the Zebrafish Metap2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    METAP2 (Methionyl Aminopeptidase 2 (METAP2))

    别名

    Metap2

    背景

    Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

    UniProt

    A5WVX8

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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