METAP2 抗体 (AA 191-464)
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Quick Overview for METAP2 抗体 (AA 191-464) (ABIN7871667)
抗原
See all METAP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 191-464
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原理
- Zebrafish Metap2 Antibody / Methionine aminopeptidase 2 / Isoforms a & b
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Metap2a/b recombinant protein (amino acids E191-R464) was used as the immunogen for the Zebrafish Metap2 antibody. This antibody will detect the a and b isoforms.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Metap2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Metap2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- METAP2 (Methionyl Aminopeptidase 2 (METAP2))
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别名
- Metap2
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背景
- Methionine aminopeptidase 2 is an enzyme that in humans is encoded by the METAP2 gene. The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.
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UniProt
- A5WVX8
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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