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STING/TMEM173 抗体 (AA 190-290)

This 小鼠 单克隆 antibody specifically detects STING/TMEM173 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7871639
发货至: 中国
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Quick Overview for STING/TMEM173 抗体 (AA 190-290) (ABIN7871639)

抗原

See all STING/TMEM173 (TMEM173) 抗体
STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

适用

  • 100
  • 33
  • 22
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 113
  • 9
小鼠

克隆类型

  • 72
  • 50
单克隆

标记

  • 60
  • 8
  • 8
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This STING/TMEM173 antibody is un-conjugated

应用范围

  • 80
  • 33
  • 29
  • 29
  • 21
  • 19
  • 18
  • 13
  • 13
  • 13
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

STING1-7438
  • 抗原表位

    • 19
    • 15
    • 13
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-290

    原理

    STING Antibody / MITA / ERIS / TMEM17

    纯化方法

    Protein A/G affinity

    免疫原

    A recombinant partial protein sequence (within amino acids 190-290) from the human protein was used as the immunogen for the STING antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the STING antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the STING antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))

    别名

    STING

    背景

    TMEM173 (transmembrane protein 173), also called MITA, ERIS and STING1, is a 379 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

    UniProt

    Q86WV6

    途径

    Activation of Innate immune Response
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