CD226 抗体 (AA 19-254)
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Quick Overview for CD226 抗体 (AA 19-254) (ABIN7871578)
抗原
See all CD226 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-254
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原理
- DNAM-1 Antibody / CD226
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids E19-A254) was used as the immunogen for the DNAM-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the DNAM-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the DNAM-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- CD226
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别名
- DNAM-1
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背景
- DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.
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UniProt
- Q15762
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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