IFI16 抗体 (AA 183-743)
Our Local Distributor
北京 101111
Quick Overview for IFI16 抗体 (AA 183-743) (ABIN7871472)
抗原
See all IFI16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 183-743
-
原理
- IFI16 Antibody / Gamma-interferon-inducible protein 16
-
纯化方法
- Antigen affinity purified
-
免疫原
- E. coli-derived recombinant human protein (amino acids E183-K743) was used as the immunogen for the IFI16 antibody.
-
亚型
- IgG2b
-
-
-
-
应用备注
- Optimal dilution of the IFI16 antibody should be determined by the researcher.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- 4 °C,-20 °C
-
储存方法
- After reconstitution, the IFI16 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- IFI16 (Interferon, gamma-Inducible Protein 16 (IFI16))
-
别名
- IFI16
-
背景
- Gamma-interferon-inducible protein Ifi-16 (Ifi-16) also known as interferon-inducible myeloid differentiation transcriptional activator is a protein that in humans is encoded by the IFI16 gene. This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
-
UniProt
- Q16666
-
途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Autophagy, Inflammasome
抗原
-