H2AFY 抗体 (AA 180-301)
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Quick Overview for H2AFY 抗体 (AA 180-301) (ABIN7871442)
抗原
See all H2AFY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 180-301
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原理
- MACROH2A1 Antibody / Core histone macro-H2A.1 / H2AFY
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids A180-K301) was used as the immunogen for the MACROH2A1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MACROH2A1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MACROH2A1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- H2AFY (H2A Histone Family, Member Y (H2AFY))
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别名
- MACROH2A1
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背景
- Core histone macro-H2A.1 is a protein that in humans is encoded by the MACROH2A1 gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O75367
抗原
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