PRMT5 抗体 (AA 18-552)
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Quick Overview for PRMT5 抗体 (AA 18-552) (ABIN7871429)
抗原
See all PRMT5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-552
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原理
- PRMT5 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids R18-A552) was used as the immunogen for the PRMT5 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PRMT5 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PRMT5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PRMT5 (Protein Arginine Methyltransferase 5 (PRMT5))
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别名
- PRMT5
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背景
- Protein arginine N-methyltransferase 5 is an enzyme that in humans is encoded by the PRMT5 gene. It is mapped to 14q11.2. This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.
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UniProt
- O14744
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途径
- Chromatin Binding, Regulation of Muscle Cell Differentiation, Ribonucleoprotein Complex Subunit Organization, Skeletal Muscle Fiber Development
抗原
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