FGF3 抗体 (AA 18-239)
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Quick Overview for FGF3 抗体 (AA 18-239) (ABIN7871402)
抗原
See all FGF3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 18-239
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原理
- FGF3 Antibody / Fibroblast growth factor 3
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids A18-H239) was used as the immunogen for the FGF3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the FGF3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FGF3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FGF3 (Fibroblast Growth Factor 3 (FGF3))
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别名
- FGF3
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背景
- INT-2 proto-oncogene protein also known as FGF-3 is a protein that in humans is encoded by the FGF3 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation.
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UniProt
- P11487
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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