GZMB 抗体 (AA 175-203)
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北京 101111
Quick Overview for GZMB 抗体 (AA 175-203) (ABIN7871301)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 175-203
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原理
- GZMB Antibody / Granzyme B
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纯化方法
- Purified
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免疫原
- A portion of amino acids 175-203 from the human protein was used as the immunogen for the GZMB antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the GZMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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别名
- GZMB
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背景
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
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UniProt
- P10144
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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