IRF1 抗体 (AA 170-315)
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Quick Overview for IRF1 抗体 (AA 170-315) (ABIN7871251)
抗原
See all IRF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-315
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原理
- IRF-1 Antibody / Interferon regulatory factor 1
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids M170-L315) was used as the immunogen for the IRF-1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the IRF-1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the IRF-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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别名
- IRF-1
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背景
- Interferon regulatory factor 1, also known as MAR is a protein that in humans is encoded by the IRF1 gene. The IRF1 gene is mapped to chromosome 5q31.1 by pulsed-field gel electrophoresis. IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
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UniProt
- P10914
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途径
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
抗原
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