Hexokinase 1 抗体 (AA 17-323)
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Quick Overview for Hexokinase 1 抗体 (AA 17-323) (ABIN7871224)
抗原
See all Hexokinase 1 (HK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 17-323
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原理
- Hexokinase 1 Antibody / HK1
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纯化方法
- Affinity purified
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免疫原
- A human recombinant protein (amino acids D17-R323) was used as the immunogen for the Hexokinase 1 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Hexokinase 1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Hexokinase 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Hexokinase 1 (HK1)
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别名
- Hexokinase 1
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背景
- Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. It is mapped to 10q22.1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.
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UniProt
- P19367
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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