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Hexokinase 1 抗体 (AA 17-323)

The 小鼠 单克隆 anti-Hexokinase 1 antibody is suitable to detect Hexokinase 1 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IF, IHC (p), FACS 和 IHC (fro).
产品编号 ABIN7871223
发货至: 中国
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Quick Overview for Hexokinase 1 抗体 (AA 17-323) (ABIN7871223)

抗原

See all Hexokinase 1 (HK1) 抗体
Hexokinase 1 (HK1)

适用

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人, 小鼠, 大鼠

宿主

  • 113
  • 53
小鼠

克隆类型

  • 94
  • 72
单克隆

标记

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This Hexokinase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

2I4
  • 抗原表位

    • 32
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 17-323

    原理

    HK1 Antibody / Hexokinase 1

    纯化方法

    Affinity purified

    免疫原

    Recombinant human protein (amino acids D17-R323) was used as the immunogen for the HK1 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the HK1 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the HK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    Hexokinase 1 (HK1)

    别名

    HK1

    背景

    Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. It is mapped to 10q22.1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

    UniProt

    P19367

    途径

    Carbohydrate Homeostasis, Warburg Effect
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