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Prohibitin 抗体 (AA 167-261)

This 小鼠 单克隆 antibody specifically detects Prohibitin in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN7871162
发货至: 中国
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Quick Overview for Prohibitin 抗体 (AA 167-261) (ABIN7871162)

抗原

See all Prohibitin (PHB) 抗体
Prohibitin (PHB)

适用

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宿主

  • 130
  • 105
小鼠

克隆类型

  • 138
  • 97
单克隆

标记

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This Prohibitin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

SPM311
  • 抗原表位

    • 95
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    AA 167-261

    原理

    Prohibitin Antibody / PHB (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    A recombinant human partial protein (amino acids 167-261) was used as the immunogen for this Prohibitin antibody.

    亚型

    IgG2c, kappa
  • 应用备注

    Optimal dilution of the Prohibitin antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Prohibitin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Prohibitin (PHB)

    别名

    Prohibitin

    背景

    Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression.

    UniProt

    P35232

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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