PAWR 抗体 (AA 160-255)
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北京 101111
Quick Overview for PAWR 抗体 (AA 160-255) (ABIN7871097)
抗原
See all PAWR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-255
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原理
- PAWR Antibody / PRKC apoptosis WT1 regulator protein / Par4
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纯化方法
- Antigen affinity purified
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免疫原
- An E.coli-derived human recombinant protein (amino acids R160-D255) was used as the immunogen for the PAWR antibody.
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亚型
- IgG
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anti-PRKC, Apoptosis, WT1, Regulator (PAWR) antibody
KD Validated PAWR 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5010 unconjugated Recombinant Antibody
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (AA 212-261) antibodyPAWR 适用: 人, 犬, 马, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (C-Term) antibodyPAWR 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) antibodyPAWR 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (AA 166-215) antibodyPAWR 适用: 人, 小鼠, 大鼠, 犬, 兔, 豚鼠, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (Middle Region) antibodyPAWR 适用: 人, 小鼠, 大鼠, 犬, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (Middle Region) antibodyPAWR 适用: 人, 小鼠, 大鼠, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) antibodyPAWR 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (C-Term) antibodyPAWR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-PRKC, Apoptosis, WT1, Regulator (PAWR) (AA 13-333) antibodyPAWR 适用: 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PAWR antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PAWR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))
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别名
- PAWR
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背景
- PRKC apoptosis WT1 regulator protein, or Prostate apoptosis response-4, is a tumor-suppressor protein coded for in the human by the PAWR gene, that induces apoptosis in cancer cells, but not in normal cells. This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases.
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UniProt
- Q96IZ0
抗原
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