MBD4 抗体 (AA 16-580)
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Quick Overview for MBD4 抗体 (AA 16-580) (ABIN7871089)
抗原
See all MBD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 16-580
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原理
- MBD4 Antibody / MED1
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纯化方法
- Affinity purified
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免疫原
- Recombinant human protein (amino acids A16-S580) was used as the immunogen for the MBD4 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the MBD4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the MBD4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
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别名
- MBD4
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背景
- Methyl-CpG-binding domain protein 4 is a protein that in humans is encoded by the MBD4 gene. It is mapped to 3q21.3. The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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UniProt
- O95243
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途径
- DNA Damage Repair
抗原
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