SETD7 抗体 (AA 159-189)
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Quick Overview for SETD7 抗体 (AA 159-189) (ABIN7871034)
抗原
See all SETD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 159-189
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原理
- SETD7 Antibody / SET7
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 159-189 from the human protein was used as the immunogen for the SETD7 antibody.
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亚型
- Ig Fraction
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anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibody
SETD7 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 适用: 人, 大鼠, 猴 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3D6G11 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 适用: 人, 大鼠, 猴 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 1B3B8 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 159-189) antibodySETD7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2763 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal S4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-218) antibodySETD7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 适用: 人 WB, ELISA, FACS, IF, ICC 宿主: 小鼠 Monoclonal s4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (C-Term) antibodySETD7 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, 猴, 斑马鱼, Bat WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting points. Titration of the SETD7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the SETD7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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别名
- SETD7
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背景
- Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.
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UniProt
- Q8WTS6
抗原
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