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TCF4 抗体 (AA 147-176)

The 兔 多克隆 anti-TCF4 antibody is suitable to detect TCF4 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN7870740
发货至: 中国
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Quick Overview for TCF4 抗体 (AA 147-176) (ABIN7870740)

抗原

See all TCF4 抗体
TCF4 (Transcription Factor 4 (TCF4))

适用

  • 81
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  • 4
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  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 54
  • 26
  • 1

克隆类型

  • 43
  • 38
多克隆

标记

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  • 5
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  • 2
  • 2
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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This TCF4 antibody is un-conjugated

应用范围

  • 63
  • 35
  • 26
  • 25
  • 9
  • 7
  • 6
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 18
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-176

    原理

    TCF4 Antibody / Transcription factor 4

    纯化方法

    Antigen affinity purified

    免疫原

    Recombinant human protein (amino acids Q147-V176) was used as the immunogen for the TCF4 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the TCF4 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the TCF4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    TCF4 (Transcription Factor 4 (TCF4))

    别名

    TCF4

    背景

    Transcription factor 4 (TCF-4) also known as immunoglobulin transcription factor 2 (ITF-2) is a protein that in humans is encoded by the TCF4 gene located on chromosome 18q21.2. This gene encodes transcription factor 4, a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed, and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome. In addition, an intronic CTG repeat normally numbering 10-37 repeat units can expand to >50 repeat units and cause Fuchs endothelial corneal dystrophy. Multiple alternatively spliced transcript variants that encode different proteins have been described.

    UniProt

    P15884

    途径

    WNT signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus
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