PGC 抗体 (AA 145-356)
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Quick Overview for PGC 抗体 (AA 145-356) (ABIN7870725)
抗原
See all PGC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 145-356
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原理
- PGC Antibody
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived human recombinant protein (amino acids Y145-N356) was used as the immunogen for the PGC antibody.
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亚型
- IgG
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anti-Pepsinogen C (PGC) (AA 100-200) antibody
PGC 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 17-392) antibodyPGC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (Internal Region) antibodyPGC 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 61-388) antibodyPGC 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 1-388) antibodyPGC 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 1-388) antibodyPGC 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 17-392) antibodyPGC 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (AA 21-120) antibodyPGC 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Pepsinogen C (PGC) (pSer15) antibodyPGC 适用: 植物 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the PGC antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PGC Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PGC (Pepsinogen C (PGC))
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别名
- PGC
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背景
- Progastricsin also known as pepsinogen C or pepsinogen II is a pepsinogen precursor of the enzyme gastricsin that in humans is encoded by the PGC gene. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.
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UniProt
- P20142
抗原
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