Surfactant Protein C 抗体 (AA 144-173)
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Quick Overview for Surfactant Protein C 抗体 (AA 144-173) (ABIN7870717)
抗原
See all Surfactant Protein C (SFTPC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 144-173
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原理
- Pulmonary surfactant-associated protein C Antibody / SFTPC
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 144-173 from the human protein was used as the immunogen for the Pulmonary surfactant-associated protein C antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Pulmonary surfactant-associated protein C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Pulmonary surfactant-associated protein C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Surfactant Protein C (SFTPC)
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别名
- Pulmonary surfactant-associated protein C
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背景
- This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
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UniProt
- P11686
抗原
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