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Surfactant Protein C 抗体 (AA 60-180)

SFTPC 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5E6A9 unconjugated
产品编号 ABIN1098147
发货至: 中国
  • 抗原 See all Surfactant Protein C (SFTPC) 抗体
    Surfactant Protein C (SFTPC)
    抗原表位
    • 21
    • 15
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 60-180
    适用
    • 57
    • 37
    • 28
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 68
    • 7
    小鼠
    克隆类型
    • 70
    • 5
    单克隆
    标记
    • 30
    • 9
    • 8
    • 8
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Surfactant Protein C antibody is un-conjugated
    应用范围
    • 50
    • 40
    • 31
    • 28
    • 16
    • 15
    • 13
    • 13
    • 7
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    纯化方法
    purified
    免疫原
    Purified recombinant fragment of human SFTPC (AA: 60-180 ) expressed in E. coli.
    克隆位点
    5E6A9
    亚型
    IgG1
    Top Product
    Discover our top product SFTPC Primary Antibody
  • 应用备注
    ELISA: 1:10000, WB: 1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified antibody in PBS with 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    4°C, -20°C for long term storage
  • Zhong, Zhou, Ann, Minoo, Liu, Banfalvi, Krishnaveni, Dubourd, Demaio, Willis, Kim, duBois, Crandall, Beers, Borok: "Role of endoplasmic reticulum stress in epithelial-mesenchymal transition of alveolar epithelial cells: effects of misfolded surfactant protein." in: American journal of respiratory cell and molecular biology, Vol. 45, Issue 3, pp. 498-509, (2011) (PubMed).

    Wang, Bridges, Na, Xu, Weaver: "Meckel-Gruber syndrome protein MKS3 is required for endoplasmic reticulum-associated degradation of surfactant protein C." in: The Journal of biological chemistry, Vol. 284, Issue 48, pp. 33377-83, (2009) (PubMed).

  • 抗原
    Surfactant Protein C (SFTPC)
    别名
    SFTPC (SFTPC 产品)
    别名
    SFTPC antibody, SPC antibody, SP-C antibody, psp-c antibody, sftp2 antibody, xSP-C antibody, Bricd6 antibody, SP5 antibody, Sftp-2 antibody, Sftp2 antibody, pro-SpC antibody, BRICD6 antibody, PSP-C antibody, SFTP2 antibody, SMDP2 antibody, surfactant protein C antibody, surfactant, pulmonary-associated protein C S homeolog antibody, surfactant, pulmonary-associated protein C antibody, surfactant associated protein C antibody, SFTPC antibody, sftpc.S antibody, sftpc antibody, Sftpc antibody
    背景

    Description: This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified. , ,

    Aliases: SP-C, PSP-C, SFTP2, SMDP2

    分子量
    21 kDa
    基因ID
    6440
    HGNC
    6440
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