TIMM8A/DDP 抗体 (AA 14-97)
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Quick Overview for TIMM8A/DDP 抗体 (AA 14-97) (ABIN7870659)
抗原
See all TIMM8A/DDP (TIMM8A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-97
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原理
- TIMM8A Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids A14-D97) was used as the immunogen for the TIMM8A antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the TIMM8A antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TIMM8A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TIMM8A/DDP (TIMM8A) (Translocase of Inner Mitochondrial Membrane 8A (TIMM8A))
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别名
- TIMM8A
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背景
- Mitochondrial import inner membrane translocase subunit Tim8 A, also known as Deafness-dystonia peptide or protein is an enzyme that in humans is encoded by the TIMM8A gene. This translocase is involved in the import and insertion of hydrophobic membrane proteins from the cytoplasm into the mitochondrial inner membrane. The gene is mutated in Mohr-Tranebjaerg syndrome/Deafness Dystonia Syndrome (MTS/DDS) and it is postulated that MTS/DDS is a mitochondrial disease caused by a defective mitochondrial protein import system. Defects in this gene also cause Jensen syndrome, an X-linked disease with opticoacoustic nerve atrophy and muscle weakness. This protein, along with TIMM13, forms a 70 kDa heterohexamer. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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UniProt
- O60220
抗原
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