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PIK3C3 抗体 (AA 14-39)

The 兔 多克隆 anti-PIK3C3 antibody is suitable to detect PIK3C3 in samples from 人. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN7870632
发货至: 中国
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Quick Overview for PIK3C3 抗体 (AA 14-39) (ABIN7870632)

抗原

See all PIK3C3 抗体
PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PIK3C3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    AA 14-39

    原理

    PI3KC3 Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 14-39 from the human protein was used as the immunogen for the PI3KC3 antibody.

    亚型

    Ig Fraction
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the PI3KC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PI3KC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))

    别名

    PI3KC3

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway.

    UniProt

    Q8NEB9

    途径

    AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy
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