PIK3C3 抗体 (AA 14-39)
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Quick Overview for PIK3C3 抗体 (AA 14-39) (ABIN7870632)
抗原
See all PIK3C3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 14-39
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原理
- PI3KC3 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 14-39 from the human protein was used as the immunogen for the PI3KC3 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the PI3KC3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PI3KC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- PIK3C3 (Phosphoinositide-3-Kinase, Class 3 (PIK3C3))
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别名
- PI3KC3
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). The regulation of the Beclin 1-PI3KC3 complex lipid kinase activity is a critical element in the autophagy signaling pathway.
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UniProt
- Q8NEB9
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途径
- AMPK Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Toll-Like Receptors Cascades, Autophagy
抗原
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