FOXA2 抗体 (AA 139-446)
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Quick Overview for FOXA2 抗体 (AA 139-446) (ABIN7870595)
抗原
See all FOXA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 139-446
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原理
- FOXA2 Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant human protein (amino acids Q139-Q446) was used as the immunogen for the FOXA2 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the FOXA2 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the FOXA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FOXA2 (Forkhead Box A2 (FOXA2))
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别名
- FOXA2
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背景
- Forkhead box protein A2 (FOXA2), also known as hepatocyte nuclear factor 3-beta (HNF-3B), is a transcription factor that plays an important role during development, in mature tissues and, when dysregulated or mutated, also in cancer. This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
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UniProt
- Q9Y261
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途径
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
抗原
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