PGK1 抗体 (AA 138-337)
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Quick Overview for PGK1 抗体 (AA 138-337) (ABIN7870590)
抗原
See all PGK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 138-337
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原理
- Zebrafish Pgk1 Antibody / Phosphoglycerate kinase 1
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纯化方法
- Antigen affinity chromatography
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免疫原
- An E.coli-derived zebrafish Pgk1 recombinant protein (amino acids N138-N337) was used as the immunogen for the Zebrafish Pgk1 antibody.
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亚型
- Ig Fraction
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应用备注
- Optimal dilution of the Zebrafish Pgk1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Zebrafish Pgk1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- PGK1 (Phosphoglycerate Kinase 1 (PGK1))
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别名
- Pgk1
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背景
- PGK1 (Phosphoglycerate Kinase 1), also known as PGKA, is an enzyme that in humans is encoded by the PGK1 gene. The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome.
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UniProt
- Q7ZV29
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途径
- Cellular Glucan Metabolic Process
抗原
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