ETS1 抗体 (AA 137-230)
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Quick Overview for ETS1 抗体 (AA 137-230) (ABIN7870570)
抗原
See all ETS1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 137-230
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原理
- ETS1 Antibody (azide and preservative free)
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纯化方法
- Protein G affinity chromatography
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免疫原
- A recombinant human partial protein (amino acids 137-230) was used as the immunogen for the ETS1 antibody.
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亚型
- IgG2b, kappa
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应用备注
- Optimal dilution of the ETS1 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store the ETS1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- ETS1 (V-Ets erythroblastosis Virus E26 Oncogene Homolog 1 (Avian) (ETS1))
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别名
- ETS1
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背景
- ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
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UniProt
- P14921
抗原
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