F2RL3 抗体 (AA 13-333)
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Quick Overview for F2RL3 抗体 (AA 13-333) (ABIN7870469)
抗原
See all F2RL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 13-333
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原理
- Par4 Antibody / Pawr / Prostate apoptosis response 4 protein
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纯化方法
- Affinity purified
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免疫原
- A mouse recombinant partial protein (amino acids T13-R333) was used as the immunogen for the Par4 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Par4 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Par4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
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别名
- Par4
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背景
- PRKC, apoptosis, WT1, regulator, also known as PAWR or Prostate apoptosis response-4 (Par-4), is a human gene. This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases.
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UniProt
- Q925B0
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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