TOP3B 抗体 (AA 128-824)
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北京 101111
Quick Overview for TOP3B 抗体 (AA 128-824) (ABIN7870416)
抗原
See all TOP3B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 128-824
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原理
- TOP3B Antibody / DNA topoisomerase 3-beta-1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids E128-R824) was used as the immunogen for the TOP3B antibody.
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亚型
- IgG
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anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-862) antibody
TOP3B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 4F11 unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-862) antibodyTOP3B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 128-824) antibodyTOP3B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-250) antibodyTOP3B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (C-Term) antibodyTOP3B 适用: 人, 小鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 1-862) antibodyTOP3B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) antibodyTOP3B 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (N-Term) antibodyTOP3B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Topoisomerase (DNA) III beta (TOP3B) (AA 826-854), (C-Term) antibodyTOP3B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB35782 unconjugated
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应用备注
- Optimal dilution of the TOP3B antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the TOP3B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TOP3B (Topoisomerase (DNA) III beta (TOP3B))
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别名
- TOP3B
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背景
- DNA topoisomerase 3-beta-1 is an enzyme that in humans is encoded by the TOP3B gene. This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
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UniProt
- O95985
抗原
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