C3 抗体 (AA 1277-1538)
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Quick Overview for C3 抗体 (AA 1277-1538) (ABIN7870406)
抗原
See all C3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1277-1538
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原理
- Complement C3 Antibody
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纯化方法
- Affinity purified
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免疫原
- A human recombinant partial protein (amino acids Q1277-E1538) was used as the immunogen for the Complement C3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Complement C3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Complement C3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- C3 (Complement Component 3 (C3))
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别名
- Complement C3
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背景
- Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.
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UniProt
- P01024
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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