FANCA 抗体 (AA 1272-1439)
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Quick Overview for FANCA 抗体 (AA 1272-1439) (ABIN7870404)
抗原
See all FANCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1272-1439
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原理
- Fanca Antibody / Fanconi anemia group A protein / FAA
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纯化方法
- Antigen affinity purified
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免疫原
- Recombinant mouse protein (amino acids E1272-F1439) was used as the immunogen for the Fanca antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the Fanca antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the Fanca antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- FANCA (Fanconi Anemia Group A Protein (FANCA))
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别名
- Fanca
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背景
- Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development, regulation of CD40 signaling pathway, and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut, liver, lung, reproductive system, and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple), acute myeloid leukemia, esophagus squamous cell carcinoma, ovarian disease (multiple), and skin melanoma. Orthologous to human FANCA (FA complementation group A).
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UniProt
- Q9JL70
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途径
- DNA Damage Repair
抗原
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