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MECOM 抗体 (AA 125-743)

The 兔 多克隆 anti-MECOM antibody is suitable to detect MECOM in samples from 人. It has been validated for WB, ELISA, IF 和 FACS.
产品编号 ABIN7870380
发货至: 中国
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Quick Overview for MECOM 抗体 (AA 125-743) (ABIN7870380)

抗原

See all MECOM 抗体
MECOM (MDS1 and EVI1 Complex Locus (MECOM))

适用

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宿主

  • 49
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克隆类型

  • 52
  • 12
多克隆

标记

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This MECOM antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 14
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    AA 125-743

    原理

    PRDM3 Antibody / MECOM / EVI1

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids E125-D743) was used as the immunogen for the PRDM3 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the PRDM3 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the PRDM3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    MECOM (MDS1 and EVI1 Complex Locus (MECOM))

    别名

    PRDM3

    背景

    MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene. The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.

    UniProt

    Q03112
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