MECOM 抗体 (AA 125-743)
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Quick Overview for MECOM 抗体 (AA 125-743) (ABIN7870380)
抗原
See all MECOM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-743
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原理
- PRDM3 Antibody / MECOM / EVI1
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids E125-D743) was used as the immunogen for the PRDM3 antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the PRDM3 antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the PRDM3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MECOM (MDS1 and EVI1 Complex Locus (MECOM))
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别名
- PRDM3
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背景
- MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene. The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
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UniProt
- Q03112
抗原
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