BACE1 抗体 (AA 125-154)
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Quick Overview for BACE1 抗体 (AA 125-154) (ABIN7870373)
抗原
See all BACE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-154
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原理
- Beta-secretase 1 Antibody / Memapsin-2 / BACE1C
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纯化方法
- Purified
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免疫原
- A portion of amino acids 125-154 from the human protein was used as the immunogen for the Beta-secretase 1 antibody.
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亚型
- Ig Fraction
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应用备注
- The stated application concentrations are suggested starting points. Titration of the Beta-secretase 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Beta-secretase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- BACE1 (Beta-secretase 1 (BACE1))
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别名
- Beta-secretase 1
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背景
- Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
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UniProt
- P56817
抗原
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