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RNF20 抗体 (AA 123-389)

This 小鼠 单克隆 antibody specifically detects RNF20 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7870352
发货至: 中国
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Quick Overview for RNF20 抗体 (AA 123-389) (ABIN7870352)

抗原

See all RNF20 抗体
RNF20 (Ring Finger Protein 20 (RNF20))

适用

  • 100
  • 56
  • 24
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 90
  • 10
小鼠

克隆类型

  • 60
  • 40
单克隆

标记

  • 44
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RNF20 antibody is un-conjugated

应用范围

  • 75
  • 30
  • 25
  • 25
  • 23
  • 22
  • 13
  • 7
  • 6
  • 1
Western Blotting (WB)

克隆位点

3C6E2
  • 抗原表位

    • 8
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 123-389

    原理

    RNF20 Antibody / BRE1A

    纯化方法

    Antigen affinity purified

    免疫原

    E. coli-derived recombinant human protein (amino acids E123-S389) was used as the immunogen for the RNF20 antibody.

    亚型

    IgG2b
  • 应用备注

    Optimal dilution of the RNF20 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the RNF20 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    RNF20 (Ring Finger Protein 20 (RNF20))

    别名

    RNF20

    背景

    E3 ubiquitin-protein ligase BRE1A is an enzyme that in humans is encoded by the RNF20 gene. The protein encoded by this gene shares similarity with BRE1 of S. cerevisiae. The protein encoded by this human gene is an E3 ubiquitin ligase that regulates chromosome structure by monoubiquitinating histone H2B. This protein acts as a putative tumor suppressor and positively regulates the p53 tumor suppressor as well as numerous histone H2A and H2B genes. In contrast, this protein also suppresses the expression of several protooncogenes and growth-related genes, including many genes that are induced by epidermal growth factor. This gene selectively suppresses the expression of some genes by interfering with chromatin recruitment of transcription elongation factor SII (TFIIS).

    UniProt

    Q5VTR2
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