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SLFN11 抗体 (AA 114-794)

The 兔 多克隆 anti-SLFN11 antibody (ABIN7870195) specifically detects SLFN11 in ELISA, WB, FACS 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN7870195
发货至: 中国
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Quick Overview for SLFN11 抗体 (AA 114-794) (ABIN7870195)

抗原

SLFN11 (Schlafen Family Member 11 (SLFN11))

适用

  • 9
  • 1

宿主

  • 9

克隆类型

  • 8
  • 1
多克隆

标记

  • 5
  • 2
  • 1
  • 1
This SLFN11 antibody is un-conjugated

应用范围

  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 6
    • 1
    • 1
    AA 114-794

    原理

    SLFN11 Antibody / Schlafen family member 11

    纯化方法

    Affinity purified

    免疫原

    An E. coli-derived human protein (amino acids P114-D794) was used as the immunogen for the SLFN11 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the SLFN11 antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Lyophilized

    缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    4 °C,-20 °C

    储存方法

    After reconstitution, the SLFN11 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • 抗原

    SLFN11 (Schlafen Family Member 11 (SLFN11))

    别名

    SLFN11

    背景

    Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene. SLFN11 is a nuclear protein that belongs to the Schlafen (SLFN) family of genes involved in cell cycle regulation and growth inhibition. Expression of SLFN11 predicts sensitivity of cancer cell lines to DNA-damaging agents. Evidence suggests that in the presence of DNA-targeted therapies, SLFN11 is recruited to stressed replication forks where it blocks replication leading to cell death. SLFN11 is being explored as a predictive biomarker for response to DNA-targeted therapies.

    UniProt

    Q7Z7L1
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