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Dystrophin 抗体 (AA 114-263)

The 小鼠 单克隆 anti-Dystrophin antibody is suitable to detect Dystrophin in samples from 人. It has been validated for IHC (p).
产品编号 ABIN7870179
发货至: 中国
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Quick Overview for Dystrophin 抗体 (AA 114-263) (ABIN7870179)

抗原

See all Dystrophin (DMD) 抗体
Dystrophin (DMD)

适用

  • 112
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宿主

  • 74
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小鼠

克隆类型

  • 88
  • 25
单克隆

标记

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This Dystrophin antibody is un-conjugated

应用范围

  • 57
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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

质量等级

Carrier-free

克隆位点

DSTN-1
  • 抗原表位

    • 55
    • 8
    • 6
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    • 4
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    • 1
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    AA 114-263

    原理

    Dystrophin Antibody / DMD (azide and preservative free)

    纯化方法

    Protein G affinity chromatography

    免疫原

    Amino acids 114-263 from the human protein were used as the immunogen for the Dystrophin antibody.

    亚型

    IgG1, kappa
  • 应用备注

    Optimal dilution of the Dystrophin antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store the Dystrophin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • 抗原

    Dystrophin (DMD)

    别名

    Dystrophin

    背景

    The DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]

    UniProt

    P11532

    途径

    Skeletal Muscle Fiber Development
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