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Dystrophin 抗体 (AA 114-263)

The 小鼠 单克隆 anti-Dystrophin antibody is suitable to detect Dystrophin in samples from 人. It has been validated for ELISA 和 IHC (p).
产品编号 ABIN7870170
发货至: 中国
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Quick Overview for Dystrophin 抗体 (AA 114-263) (ABIN7870170)

抗原

See all Dystrophin (DMD) 抗体
Dystrophin (DMD)

适用

  • 112
  • 18
  • 17
  • 3
  • 2

宿主

  • 74
  • 39
小鼠

克隆类型

  • 88
  • 25
单克隆

标记

  • 68
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
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This Dystrophin antibody is un-conjugated

应用范围

  • 57
  • 32
  • 29
  • 27
  • 26
  • 12
  • 10
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

DMD-3676
  • 抗原表位

    • 55
    • 8
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 114-263

    原理

    DMD Antibody / Dystrophin

    纯化方法

    Protein A/G affinity

    免疫原

    A portion of amino acids 114-263 from the human protein was used as the immunogen for the DMD antibody.

    亚型

    IgG2b, kappa
  • 应用备注

    Optimal dilution of the DMD antibody should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.2 mg/mL

    缓冲液

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the DMD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Dystrophin (DMD)

    别名

    DMD

    背景

    Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.

    UniProt

    P11532

    途径

    Skeletal Muscle Fiber Development
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