Dystrophin 抗体 (AA 114-263)
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Quick Overview for Dystrophin 抗体 (AA 114-263) (ABIN7870169)
抗原
See all Dystrophin (DMD) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
克隆位点
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抗原表位
- AA 114-263
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原理
- DMD Antibody / Dystrophin (azide and preservative free)
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纯化方法
- Protein A/G affinity
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免疫原
- A portion of amino acids 114-263 from the human protein was used as the immunogen for the DMD antibody.
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亚型
- IgG2b, kappa
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anti-Dystrophin (DMD) (AA 346-635) antibody
DMD 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) (AA 1-635) antibodyDMD 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3A11 unconjugated
anti-Dystrophin (DMD) (AA 114-263) antibodyDMD 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal DMD-3242 unconjugated
anti-Dystrophin (DMD) (AA 3076-3404) antibodyDMD 适用: 人, 小鼠, 大鼠 IHC, WB, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) (AA 3048-3328) antibodyDMD 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) (AA 114-263) antibodyDMD 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal DMD-3241 unconjugated
anti-Dystrophin (DMD) (AA 114-263) antibodyDMD 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal DMD-3245 unconjugated
anti-Dystrophin (DMD) (AA 253-597) antibodyDMD 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dystrophin (DMD) antibodyDMD 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 4B10 unconjugated Recombinant Antibody
anti-Dystrophin (DMD) (AA 3400-3558) antibodyDMD 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the DMD antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
- Aliquot the DMD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Dystrophin (DMD)
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别名
- DMD
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背景
- Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002 % of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.
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UniProt
- P11532
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途径
- Skeletal Muscle Fiber Development
抗原
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