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POLG 抗体 (AA 1120-1148)

The 兔 多克隆 anti-POLG antibody (ABIN7870144) specifically detects POLG in WB, IHC (p), IF 和 FACS. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN7870144
发货至: 中国
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Quick Overview for POLG 抗体 (AA 1120-1148) (ABIN7870144)

抗原

See all POLG 抗体
POLG (Polymerase (DNA Directed), gamma (POLG))

适用

  • 49
  • 23
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  • 1
  • 1
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人, 小鼠

宿主

  • 49
  • 2

克隆类型

  • 44
  • 7
多克隆

标记

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  • 2
  • 2
  • 1
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  • 1
  • 1
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  • 1
  • 1
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This POLG antibody is un-conjugated

应用范围

  • 40
  • 13
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  • 11
  • 8
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  • 4
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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1120-1148

    原理

    POLG Antibody

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 1120-1148 from the human protein was used as the immunogen for the POLG antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting points. Titration of the POLG antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the POLG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    POLG (Polymerase (DNA Directed), gamma (POLG))

    别名

    POLG

    背景

    Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

    UniProt

    P54098
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