POLG 抗体 (AA 1120-1148)
Our Local Distributor
北京 101111
Quick Overview for POLG 抗体 (AA 1120-1148) (ABIN7870144)
抗原
See all POLG 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1120-1148
-
原理
- POLG Antibody
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 1120-1148 from the human protein was used as the immunogen for the POLG antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- The stated application concentrations are suggested starting points. Titration of the POLG antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the POLG antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- POLG (Polymerase (DNA Directed), gamma (POLG))
-
别名
- POLG
-
背景
- Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
-
UniProt
- P54098
抗原
-