RAD51C 抗体 (AA 11-342)
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Quick Overview for RAD51C 抗体 (AA 11-342) (ABIN7870078)
抗原
See all RAD51C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-342
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原理
- RAD51C Antibody
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纯化方法
- Antigen affinity purified
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免疫原
- E. coli-derived recombinant human protein (amino acids Q11-K342) was used as the immunogen for the RAD51C antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the RAD51C antibody should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- 4 °C,-20 °C
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储存方法
- After reconstitution, the RAD51C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))
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别名
- RAD51C
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背景
- RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.
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UniProt
- O43502
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途径
- DNA Damage Repair
抗原
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